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Table 6: Methodological quality of quantitative studies reporting correlations and associations

From: Young carers: growing up with chronic illness in the family - a systematic review 2007-2017

1. Population

1.

2.

3.

4.

5.

6.

7.

8.

9

 1.1 Is the source population or source area well described?

+

++

++

++

++

++

++

 1.2 Is the eligible population or area representative of the source population or area?

++

++

++

+

++

++

+

+

++

 1.3 Do the selected participants or areas represent the eligible population or area?

+

+

+

+

+

+

++

2. Method of selection of exposure (or comparison) group

 2.1 Selection of exposure (and comparison) group. How was selection bias minimised?

NR

NR

++

 2.2 Was the selection of explanatory variables based on a sound theoretical basis?

++

++

++

++

+

++

++

++

++

 2.3 Was the contamination acceptably low?

NA

NA

NA

NA

NA

NA

NA

NA

++

 2.4 How well were likely confounding factors identified and controlled?

NR

NR

+

 2.5 Is the setting applicable to the UK? (for this review: Germany)

+

+

+

+

+

+

+

+

+

3. Outcomes

 3.1 Were the outcome measures and procedures reliable?

++

++

++

++

++

++

++

++

+

 3.2 Were the outcome measurements complete?

++

++

++

++

++

++

++

++

+

 3.3 Were all the important outcomes assessed?

++

++

++

++

++

++

++

++

+

 3.4 Was there a similar follow-up time in exposure and comparison groups?

NA

NA

NA

+

NA

NA

NA

NA

+

3.5 Was follow-up time meaningful?

NA

NA

NA

++

NA

NA

NA

NA

+

4. Analysis

 4.1 Was the study sufficiently powered to detect an intervention effect (if one exists)?

NA

NA

NA

NA

NA

NA

NA

NA

++

 4.2 Were multiple explanatory variables considered in the analyses?

++

++

++

++

++

++

++

++

++

 4.3 Were the analytical methods appropriate?

++

++

++

++

++

++

++

++

++

 4.6 Was the precision of association given or calculable? Is association meaningful?

++

++

++

++

++

++

++

++

++

5. Summary

 5.1 Are the study results internally valid (i.e. unbiased)?

++

++

++

++

+

++

++

++

++

 5.2 Are the findings generalisable to the source population (i.e. externally valid)?

+

++

+

++

+

+

+

+

++

  1. 4.4 and 4.5 do not exist in original checklist (National Institute for Health and care Excellence, 2012)